Review Article: The Health Effects of Vitamin C Supplementation: A Review
Bendich A; Langseth L
Paramus, N.J.;Palisades, N.Y.
Review Article: The Health Effects of Vitamin C Supplementation: A Review
J. Am. Coll. Nutr. 14, No. 2, 124-136 1995
Higher than RDA intakes of vitamin C have been associated with several indices of lowered cardiovascular disease risk including increases in HDL, and decreases in LDL oxidation, blood pressure and cardiovascular mortality. *The safety of higher than RDA intakes of vitamin C is confirmed in eight placebo-controlled , double-blind studies and six non-placebo clinical trials in which up to 10,000 mg of vitamin C was consumed daily for up to 3 years. There are no clinical data which suggest that vitamin C´s enhancement of non-heme iron absorption in individuals with low iron status could be a critical factor in the possible increased risk of heterozygous hemochromatosis-related cardiovascular disease.
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